What is RU486? What is the use of RU486?

RU486 has a remarkable application in concluding an early pregnancy of less than 7 weeks of gestation. Today, this abortion pill became a most successful and admired abortion method in annihilating unwanted or unplanned pregnancies because of its safety and reliability. RU486 abortion pill is more safe, efficient, reliable, trouble-free, and economical means of abortion than surgical method. Above all, RU486 respects the privacy of a woman undergoing an abortion means she can easily terminate her pregnancy without disclosing the news of her abortion.

How RU486 helps to execute an abortion?

RU486 comprises of an FDA-approved generic drug called Mifepristone (an antiprogestin). It creates an obstruction in the functioning of the female hormone called progesterone that inhibits the further growth of a fetus. The decline in the body's progesterone level causes the shedding of the lining of uterine wall that causes the detachment of the placenta from the uterine wall resulting in the removal of a fetus from the mother's womb. Along with causing relaxation and dilation of the cervix, Mifepristone expels a fetus out of the mother's womb by increasing the contraction of the uterine wall.

How can you use RU486 to execute an abortion?

RU486 pack comprises of three Mifepristone pills (each 200mg) and follows this dosing regimen to execute an abortion with aid of RU486. At first, you need to ingest three Mifepristone pills orally on an empty stomach, with sufficient amount of water. After two days, you should confirm your abortion by following an ultrasonography test. If you are still pregnant, then you need to take two Misoprostol pills (each 200mcg) via the oral or vaginal route. Again, after two days, you should finally confirm your abortion by following an ultrasonography test.


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When should you not use RU486?

You should never use RU486 abortion pills to execute an abortion if you are facing any of these medical cases:

  1. Ectopic pregnancy or tubal pregnancy (pregnancy outside the uterus)
  2. Chronic adrenal failure or Addison dysfunction
  3. Porphyria
  4. Undiagnosed development in abdomen
  5. Severe undiagnosed uterine bleeding
  6. Hypersensitive reactions with generic Mifepristone or other ingredients of RU486

What are the side effects of RU486?

Some of the side effects that users of RU486 might experience while using executing an abortion with this medicine:

  1. Weariness
  2. Stomach cramping or ache
  3. Severe vaginal bleeding
  4. Lightheadedness
  5. Diarrhea
  6. Queasiness
  7. Back pain
  8. Vomiting

What are the possible drug interactions of RU486?

Some drugs show drug interaction with generic Mifepristone, so do not use RU486 medicine along with these following drugs:

  1. Anticoagulants: Warfarin
  2. Corticosteroids: Hydrocortisone
  3. Azole antifungals: Itraconazole, Ketoconazole 
  4. Erythromycin 
  5. Carbamazepine, Phenobarbital
  6. Dexamethasone
  7. Rifampin
  8. St. John's Wort

What are the safety measures to be followed while using RU486?


  1. RU486 is not a safe and effective in concluding a pregnancy is over 7 weeks since the last menstrual cycle started. 
  2. Limit the ingestion of alcohol, grapefruits or juices while executing an abortion with RU486 pill. 
  3. Hold back yourself from performing powerful physical exercise and sensual intercourse sessions for some weeks after the carrying out of an abortion. 
  4. You are required to ingest nutritious diets during or after an abortion for quick health recovery.
  5. You are required to avoid anticoagulants during an abortion; otherwise, it can cause severe vaginal bleeding.

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